Railway companies of Mississippi

List of railway companies in the American state of Mississippi.

Class I railways

 * Amtrak (AMTK), passenger on freight lines
 * Burlington Northern & Gulf Railroad (BNG), freight
 * Chesapeake Southern Railway (CHS), freight
 * Gulf & Atlantic Railway (GA), freight and passenger
 * Kansas City-Santa Fe Railroad (KCSF), freight
 * New York Western Railroad (NYW), freight
 * Pennsylvania Seaboard Railroad (PS), freight
 * Union Pacific Railroad (UP), freight

Regional railways

 * West Tennessee Railroad (WTNN)

Shortline and terminal railways

 * Alabama Southern Railroad (ABS), freight
 * Mississippi Central Railroad (MSCI), freight

Defunct railways
Years shown here refer to the period in which a given company operated in Mississippi; they may have existed elsewhere before or after these years.